The Pathogenesis of Kawasaki Disease and Superantigens

Pathogenesis of Kawasaki disease: the central role of TNF-α

Genetics insights into the pathogenesis of Kawasaki disease.

First described by a Japanese pediatrician in 1967, Kawasaki disease (KD) is an acute vasculitis of infancy and childhood that has become the leading cause of acquired heart disease in children in the developed world.1,2 No single etiologic agent of KD has been found despite 4 decades of investigation.3 In the absence of a causative agent or definitive laboratory test, its diagnosis is made by ...

S100 proteins in the pathogenesis of Kawasaki disease.

COVID-19 and Kawasaki Disease: Kawasaki-Like Disease Case Report in Iran

During the Coronavirus disease 2019 (COVID-19) pandemic, children are less affected than adults, and underlying conditions and older age are associated with severe disease. Following the SARS-CoV-2 pandemic, outbreaks of cases with Kawasaki-like disease and a few others with the multisystem inflammatory syndrome in children related to COVID-19 (MIS-C) have been reported. Here, we report a two-y...

Epidemiological and Clinical Characteristics of Kawasaki Disease in Mazandaran

Background and purpose: Kawasaki is an acute childhood vasculitis of unknown cause that if left untreated can cause coronary aneurysms in 25% of cases. The disease is reported as the leading cause of acquired heart disease in children in developed countries. The purpose of this study was to investigate the epidemiological and clinical features of Kawasaki disease in northern Iran. Materials an...